Marker check · 4 questions

Gut & colon health

Colorectal cancer is the second-deadliest cancer, and one of the most preventable: in the 23-year NEJM polypectomy cohort, removing precancerous polyps at colonoscopy cut colorectal-cancer deaths roughly in half. Diet does heavy lifting here — the highest-fiber eaters show 15–16% lower all-cause mortality and colorectal cancer risk (Reynolds 2019), while daily processed meat measurably raises colon-cancer risk. Rates are rising in adults under 50, which is why screening now starts at 45 and persistent gut symptoms deserve a doctor, not a guess.

The research

  • Zauber et al., NEJM 2012 — polypectomy, ~53% lower CRC mortality
  • Reynolds et al., Lancet 2019 — highest fiber at 25–29g/day: all-cause −15%, CRC −16%
  • Bouvard et al. (IARC), Lancet Oncol 2015 — processed meat +18% CRC per 50g/day
  • Siegel et al., CA Cancer J Clin 2023 — early-onset CRC rising since the 1990s
  1. 1. How much fiber do you eat (whole grains, beans, fruit, vegetables)?

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  2. 2. How often do you eat red meat?

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  3. 3. Are you up to date on colorectal screening (recommended from 45)?

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  4. 4. Any persistent gut symptoms (blood, pain, big bowel-habit changes)?

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